Congress is facing the most significant and transformational opportunity to strengthen the U.S. defense industrial base (DIB) since the end of World War II. The heritage equipment that the United States has provided to Ukraine for its self-defense in the face of the brazen and illegal invasion by Russian forces in 2022 needs to be replenished to ensure the United States is postured to continue to deter its adversaries. The new hardware will be produced at factories across the nation. Of the $113 billion appropriated by Congress to date related to the conflict in Ukraine, as much as $68 billion is destined to be invested here at home. U.S. support for Ukraine thus offers a once-in-a-generation opportunity to sustain a demand signal to address long-standing weaknesses in U.S. DIB systems generally and ordnance and missile production specifically. Examining how U.S. military assistance to Ukraine is being spent and where funds for the U.S. industrial base relevant to Ukraine and future U.S. needs are being invested can help demonstrate how Russia’s war can establish a long-term incentive structure to revitalize the DIB.